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High-throughput lead optimization in drug discovery / edited by Tushar Kshirsagar

(Critical reviews in combinatorial chemistry)

データ種別	図書
出版者	Boca Raton : CRC Press
出版年	c2008
著者標目	Kshirsagar, Tushar

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配架場所	巻　次	請求記号	登録番号	状　態	コメント	ISBN	刷　年	予約	利用注記
白金単行本書架		499.3\|\|Kr9	21042966

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大きさ	ix, 243 p. : ill. ; 26 cm
内容注記	Application of parallel synthesis to the optimization of inhibitors of the ZipA-FtsZ protein-protein interaction / Lee D. Jennings Case studies of parallel synthesis in hit identification, hit exploration, hit-to-lead, and lead optimization programs / Alexander Ernst and Daniel Obrecht A successful application of parallel synthesis to computer-assisted structural optimization of new leads targeting human immunodeficiency virus-1 reverse transcriptase : the case of acylthiocarbamates and thiocarbamates / Angelo Ranise, Andrea Spallarossa, and Sara Cesarini How high-throughput medicinal chemistry can expedite lead discovery, lead optimization, and beyond / Rongshi Li Rapid lead identification of inhibitors of adenine nucleotide translocase: a case study of applying combinatorial chemistry techniques in drug discovery / Yazhong Pei, Walter H. Moos, and Soumitra Ghosh Parallel synthesis of anticancer, antiinflammatory, and antiviral agents derived from L- and D-amino acids / Robert C. Reid and David P. Fairlie Application of solid-phase parallel synthesis in lead optimization studies / Bijoy Kundu High-throughput solid-phase synthesis of nucleoside-based libraries in the search for new antibiotics / Dianqing Sun and Richard E. Lee
件　名	LCSH:High throughput screening (Drug development) LCSH:Combinatorial chemistry LCSH:Drug development MESH:Combinatorial Chemistry Techniques MESH:Drug Design MESH:Databases, Genetic MESH:Gene Library
一般注記	Includes bibliographical references and index HTTP:URL=http://www.loc.gov/catdir/enhancements/fy0829/2007035804-d.html Information=Publisher description HTTP:URL=http://www.loc.gov/catdir/toc/fy0804/2007035804.html Information=Table of contents
分　類	LCC:RS419.5 NLM:QV 744 DC22:615/.19
書誌ID	BB10076801
本文言語	und
巻冊次	hardback : alk. p ; ISBN:9780849372681 hardback : alk. pape ; ISBN:0849372682
NCID	GB3839858X

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